"He's been a very consistent player. Jones told 105.3 The Fan on Tuesday that Prescott is not expected to go on short-term injured reserve, which would mean a minimum four-week absence according to IR rules. The decision to sign Shepley is to help add depth to a needy offensive line, while Ollison will join a running backs room that is far from deficient. With their two available practice squad elevations, the Cowboys elevated quarterback Will Grier and rookie center Alec Lindstrom. The official source for NFL news, video highlights, fantasy football, game-day coverage, schedules, stats, scores and more. Nature 2013; Corn PG, Heath EI, Zurita A et al: Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1-2 trial. Clinicians should offer germline and somatic testing to inform discussions around prognosis; however, germline testing may also be used to counsel patients regarding their family risk of associated malignancies. Am J Prev Med 2001; Shea BJ, Reeves BC, Wells G et al: AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. Washington suffered a broken foot in the first week of camp back in July and has been on IR ever since. This is Gallup's first practice since undergoing knee surgery in February to repair a torn ACL. Hope T, Goodman J, Allen I et al: Meta-analysis of 68Ga-PSMA-11 PET accuracy for the detection of prostate cancer validated by histology. Clin Prostate Cancer 2003; Abdel-Rahman: Prostascore: a simplified tool for predicting outcomes among patients with treatment-naive advanced prostate cancer. "I know at the conclusion of the surgery, the surgeon was very optimistic. It's been a really good fit - the young players enjoy their time with him.". Here is a recap of his injury trouble in 2021 and an exploration of his stats from this season compared to last. Penson DF, Armstrong AJ, Concepcion R et al: Enzalutamide versus bicalutamide in castration-resistant prostate cancer: the STRIVE trial. In a trial of 1,468 men receiving ADT for prostate cancer,146patients were randomly assigned to denosumab (60mg every 6 months) versus placebo. As such, sipuleucel-T should only be considered for patients with asymptomatic or minimally symptomatic mCRPC. Lancet Oncol. 25. Br J Med Surg Urol 2012; Giovacchini G, Incerti E, Mapelli P et al: [C]Choline PET/CT predicts survival in hormone-naive prostate cancer patients with biochemical failure after radical prostatectomy. Practical Assessment, Research & Evaluation 2007; Siegel RL, Miller KD, Jemal A: Cancer statistics, 2019. Urology 2000; Gravis G, Boher JM, Joly F et al: Androgen deprivation therapy (ADT) plus docetaxel versus ADT alone in metastatic non castrate prostate cancer: impact of metastatic burden and long-term survival analysis of the randomized phase 3 GETUG-AFU15 trial. Both returned to practice on Friday, however, and though it was in a limited capacity, it supports the expectation that they'll take the field in Week 13 - along with Diggs saying he "feels a lot better" than earlier in the week - while DeMarcus Lawrence is a full-go with injury designation at all on Friday. Recommendations include weight bearing exercises, muscle building exercises, balance exercises, smoking cessation, reduction of alcohol intake, and adequate intake of calcium and vitamin D.144The estimated daily calcium requirement is 1,000 mg to 1,200 mg from food and supplements. Of the 921 patients of this trial, those receiving treatment were given 6 intravenous injections with a dose of 50 kBq per kilogram of body weight every four weeks. In the TOPARP-A trial, heavily-treated mCRPC patients treated with olaparib were much more likely to respond in the setting of a DDR alteration.39 The response rate was 88% in biomarker positive patients and 6% in biomarker negative patients. A muscle injury on the eve of Rangers Champions League visit has spelt the end of Arthurs 2022, after undergoing surgery on the issue. Dr. Geoff Watson of theBone and Joint Institute explained toA to Z Sports Nashvillethat most fractures of that nature are repaired with just a screw. Henry's was repaired with a screw and a plate. Currentlytheir role in the management of advanced prostate cancer is not entirely clear. Yet, Jalen Tolbert was no active for Sunday's game with the Bucs, passed over by an undrafted rookie and a fifth-round pick from last year. Several key areas of future research need emphasis to improve clinical care and provide a path to better patient outcomes with advanced prostate cancer. The four-time Pro Bowl linebacker neared a return to action against his former team, the Minnesota Vikings, but reaggravated the injury the day prior and was instead forced to the inactives list for that matchup. Prostate Suppl 1994; Tyrrell CJ, Iversen P, Tammela T et al: Tolerability, efficacy and pharmacokinetics of bicalutamide 300 mg, 450 mg or 600 mg as monotherapy for patients with locally advanced or metastatic prostate cancer, compared with castration. "In the meantime, we're doing a lot of work regarding [his] physical conditioning - things like that - so all of that is working. PSMA-based therapeutics are another potential treatment currently emerging from the ability to target PSMA expressed on the surface of cancer cells. Injury: Jones fracture. These imaging modalities identify sites of recurrent prostate cancer with superior specificity and sensitivity compared to conventional imaging.157-159These findings are already impacting treatment planning by altering physician decision making, but they have yet to demonstrate a clear benefit specific to patient outcomes.160Use of these imaging agents will allow for identification of metastatic sites not otherwise seen with conventional imaging. N Engl J Med 2017; Finianos A, Gupta K, Clark B et al: Characterization of differences between prostate cancer patients presenting with de novo versus primary progressive metastatic disease. Parsons is now tied for second in NFL history with most sacks (15.0) in his first 17 games of his career. Air can be introduced into the circulation during surgical procedures, lung over-expansion injury, decompression, and a few other causes.Air embolisms may also occur in the xylem of vascular plants, As radium-223 targets bone only and is not associated with a PSA decline in a majority of patients, it is imperative for the clinician to carefully assess the patient on a monthly basis. Sipuleucel-T is not associated with objective anti-tumor activity; its use is not appropriate for patients with large tumor burdens, those with visceral disease or with rapidly progressive disease. The former fourth-round pick saw his rookie season mostly derailed in 2021 by a torn ACL, but has now been available for much of training camp after not being placed on the physically unable to perform (PUP) list in July. Eur J Cancer 2015; Fu AZ, Tsai HT, Haque R et al: Mortality and androgen deprivation therapy as salvage treatment for biochemical recurrence after primary therapy for clinically localized prostate cancer. 1 seed, Henry will presumably be able to play in the Divisional Round of the NFL playoffs. Lancet Oncol 2019. Israel Cando | TFC News Vancouver Dec 09 08:31 PM. J Clin Oncol 2019; Chi KN, Protheroe A, Rodriguez-Antolin A et al: Patient-reported outcomes following abiraterone acetate plus prednisone added to androgen deprivation therapy in patients with newly diagnosed metastatic castration-naive prostate cancer (LATITUDE): an international, randomised phase 3 trial. Recent evidence suggests that cell-free DNA sequencing methods may allow MSI status to be determined with liquid biopsies. The durability of these treatments is being evaluated in multiple prospective clinical studies. N Engl J Med 2004; Scher HI, Fizazi K, Saad F et al: Increased survival with enzalutamide in prostate cancer after chemotherapy. Prescott and cornerback Jourdan Lewis (hamstring) do not have injury designations for Week 1, which means they're set to play Sunday. And that's what we wanted.". Specifically, cancer-specific survival among men found to be harboring a BRCA2 mutation was found to be half of that among men without a defect in DDR (17.4 versus 33.2months, p=0.027).118Mutations in tumor suppressor genes have also been found to be associated with adverse outcomes among men with prostate cancer. But just how difficult was it for him to put forth this impressive, comeback season? The hamstring (injury) really played a factor in this. Lancet Oncol 2020; Alexandrov LB, Nik-Zainal S, Wedge DC et al: Signatures of mutational processes in human cancer. 10:46 a.m. - Michael Gallup continues to progress in his recovery from a torn ACL suffered in 2021 in "outstanding" fashion, as owner and general manager Jerry Jones labeled it on Friday, but the Hall of Famer wanted to clear the air on recent comments regarding the Super Bowl that were viewed as a hint that Gallup is potentially ready to play in the regular season opener - the veteran wideout still needing some time to become game-ready. Lancet 2010; Parker C, Nilsson S, Heinrich D et al: Alpha emitter radium-223 and survival in metastatic prostate cancer. Smith appears to be the leading candidate to replace left tackle Tyron Smith (hamstring) in the starting lineup Sept. 11 against the Bucs. 10:55 a.m. - Quarterback Dak Prescott is back at The Star after undergoing right thumb surgery Monday, and head coach Mike McCarthy echoed Jerry Jones' comments that the team is optimistic about Prescott's return timeline following the procedure to repair the thumb fracture. The former sixth-round pick had a breakout season for Dallas in 2020 before seeing his 2021 season mostly derailed by injury, but he showed on Sunday that he's not only completely healthy, but that he's back to being an impact player as well. The previously outlined plan will start the All-Decade tackles three-week activation clock. It's also worth noting that the surgery Henry had to repair the Jones fracture was a bit different than most surgeries of that nature. His timeline is expected to be anywhere from three to four months, all thanks to a training injury sustained in a normal situation.. Once activated, Henry will have a maximum of three weeks to practice before he rejoins the 53-man roster. Methods Guide for Effectiveness and Comparative Effectiveness Reviews. Game reps will definitely help because there's no better way to get ready for a game than to play in a game - getting in game shape will be one of the main things - but right now I'm prepared for Week 1.". Patients who received docetaxel plus prednisone every three weeks in TAX-327 had significantly better survival than those receiving mitoxantrone (HR for death: 0.76; p=0.009). Median overall survival in cohort A was 18.5 months with olaparib compared to 15.1 months in the control group. Overall though, it seems that Henry's injury healed nicely and has been put well in the rearview mirror. 10:34 p.m. - Dak Prescott entered the game tied for fifth all-time in franchise history in touchdown passes. Lewis was moving very well in individual drills,, a sign he's likely close to being 100% - barring an unexpected turn of events. BMJ 2017; 358. 4:29 p.m. - The Cowboys were hoping to get fifth-round pick John Ridgeway back on the practice squad this week but he was claimed by Washington. Matt Farniok has replaced him at left guard. Spurs rookie small forward Malaki Branham, the No. For AR-V7, the initial seminal study by Antonarakis and colleagues showed that high expression of AR-V7 in CTCs was associated with rapid disease progression in men with mCRPC starting enzalutamide or abiraterone acetate.163Other studies have confirmed these findings using different platforms for measuring AR-V7 expression in circulation and also showed that patients with high AR-V7 expression may still respond well to chemotherapy.164-167Two CLIA-certified laboratory developed tests are currently commercially available, and the PROPHECY trial prospectively validated these tests in an mCRPC population while also showing that some discrepancies exist in test results between these two assays.168Importantly, the vast majority of patients were AR-V7-negative by both assays. Sipuleucel-T is an immunotherapy for the management of mCRPC. WebAbout Our Coalition. Given the dramatic increase in available therapies for advanced prostate cancer over the past 10 years, there is a renewed urgency to identify predictive biomarkers that can guide treatment selection. WebAn air embolism, also known as a gas embolism, is a blood vessel blockage caused by one or more bubbles of air or other gas in the circulatory system. Radium-223 is an -emitting radiopharmaceutical capable of inducing double strand DNA breaks in cancer cells while minimizing exposure to surrounding marrow. 2:44 p.m. - The Cowboys have officially ruled wide receiver Michael Gallup out of Sunday's game against the Bengals, though Gallup continues to move closer toward a return to game action. The majority of patients will receive one ART targeted therapy with abiraterone acetate plus prednisone or enzalutamide and docetaxel chemotherapy. Password: Password requirements: 6 to 30 characters long; ASCII characters only (characters found on a standard US keyboard); must contain at least 4 different symbols; at least 1 number, 1 uppercase and 1 lowercase letter; not based on your username or email address. The rate of pathologic fractures was also lower compared to placebo (13.1% with zoledronic acid versus 22.1% for placebo). randomly assigned 1,195 patients who had previously received docetaxel in a 2:1 ratio to receive 5 mg of prednisone twice daily with either 1,000 mg abiraterone acetate or placebo. A Jones fracture is a type of fracture in your foot. Eur Urol 2019; Kane CJ, Amling CL, Johnstone PA et al: Limited value of bone scintigraphy and computed tomography in assessing biochemical failure after radical prostatectomy. On Thursday, the team signed Qadree Ollison and Dakoda Shepley to the unit, officially filling out the 17-man group, with both players set to join the final practice of the week. Adverse events of grade 3 or higher occurred in 56.3% of patients receiving cabazitaxel and in 52.4% of those receiving an androgen-signaling-targeted inhibitor. Ice causes blood vessels to constrict, which reduces inflammation, and A rookie defensive tackle from Arkansas, Ridgeway spent the first week of the season on the 53-man roster but was waived on Saturday to make space for players needed for injuries. If Morant doesnt end up being activated for Tuesdays contest, hell get a couple extra days off before Memphis hosts New Orleans on Friday night, so hed be well positioned to play in that game. WebHeadache, dizziness, confusion, and fatigue tend to start immediately after an injury, but resolve over time. A SEER-based study. 3:07 p.m. - The Cowboys added safety Jayron Kearse (neck) to Friday's injury report and officially listed him as questionable for Sunday's opener against Tampa Bay. Suffice to say that the Titans' plan and timeline worked for Henry. Fine aside, the 63 lead guard out of Murray State is having a terrific fourth season for the 13-9 Grizzlies thus far, averaging a career-high 28.2 PPG on .460/.366/.743 shooting splits. Alexander-Arnold played the remainder of the first half after an inversion ankle sprain midway through, but swelling and pain prevented him from coming out for the second half at Arsenal. "Cooper [Rush] stepped in and did a great job for us last year when Dak had to sit out a game. --------------------------------------- Kelvin Joseph, Height: 6-1Weight: 192 lbsCollege: Kentucky. While Banes return isnt imminent (hes listed as out on Tuesday and will likely miss another week or two), having Morant back would be a major boon for Memphis against a Sacramento team riding a six-game win streak. Liverpool have just added three new names to their injury list, taking the total number of players currently sidelined to six. Originally listed as doubtful for Tuesday vs. Sacramento, Morant has been upgraded to questionable, the Grizzlies announced this morning (via Twitter). "I don't have anything definitive there," he told 105.3FM the Fan. He remains one of the NFL's best running backs and has surely ensured that no regression has come as a result of his injury. In the double-blind, phase 3 PREVAIL study, Beer et al. Lancet Oncol 2019; Morris MJ, Rowe SP, Gorin MA et al: Diagnostic performance of. We will guide you on how to place your essay help, proofreading and editing your draft fixing the grammar, spelling, or formatting of your paper easily and cheaply. Lowrance WT, Breau RH, Chou R et al: Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I. J Urol 2021; Lowrance WT, Breau RH, Chou R et al: Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART II. Injury: Calf 2019; Bach-Gansmo T, Nanni C, Nieh PT et al: Multisite experience of the safety, detection rate and diagnostic performance of fluciclovine (18F) positron emission tomography/computerized tomography imaging in the staging of biochemically recurrent prostate cancer. As it stands, Diggs and Gallup are expected to have plenty of time to rest and recover in time to face the Colts on Sunday, and linebacker Anthony Barr (hamstring) has a chance at joining them for what would be his first game snaps since Week 8 after reaggravating his injury recently. WebGet breaking NBA Basketball News, our in-depth expert analysis, latest rumors and follow your favorite sports, leagues and teams with our live updates. Lancet 2011; Himelstein AL, Foster JC, Khatcheressian JL et al: Effect of longer-Interval vs standard dosing of zoledronic acid on skeletal events in patients with bone metastases. WebAn air embolism, also known as a gas embolism, is a blood vessel blockage caused by one or more bubbles of air or other gas in the circulatory system. A meta-analysis145included 15 trials of 2,634 men with prostate cancer receiving ADT (with or without bone metastases) randomized to receive a bisphosphonate versus placebo. In need of a fullback, Gifford was inserted into a goal-line package, leading the way for Tony Pollard's 1-yard touchdown run in the first quarter. As Evan Barnes of The Memphis Commercial Appeal details, Chandler has taken advantage this season of the opportunity to lean from the two veteran point guards ahead of him on the depth chart, but admits he has had to adjust to not playing regularly. ------------------------------------ Dec. 2 UpdatesTrevon Diggs, Height: 6-2Weight: 195 lbsCollege: Alabama. Data from the STRIVE and TERRAIN trials107,108suggest that bicalutamide is not a reasonable option for treatment of men with nmCRPC. Local control in the SWOG 1802 study may consist of surgery, radiation, or both, based on physician discretion and patient choice. J Urol. That will answer itself. --------------------------------------- Jayron Kearse, Height: 6-4Weight: 215 lbsCollege: Clemson. Nov. 1: Henry is placed on IR by the Titans. Nov. 2: The Titans officiallysign Adrian Peterson and D'Onta Foreman to the practice squad. PARP inhibitors leverage defects in DNA repair to provide a survival advantage in men with mCRPC who have mutations in DNA repair enzymes central to homologous recombination DNA repair. Joseph suffered a concussion in the preseason finale against the Seahawks and was relegated to concussion protocol to that point. This allows clinicians to monitor disease status and should be performed every three to six months. Prostate Cancer Prostatic Dis 2017; Sternberg CN, Fizazi K, Saad F et al: Enzalutamid and survival in nonmetastatic, castration-resistant prostate cancer. Monitoring of men with nmCRPC should include serial measurements of PSA, whether patients are receiving ADT alone or ADT with an additional AR directed therapy (apalutamide, darolutamide, enzalutamide). In the enzalutamide group, the median OS was 67.0 months (95%CI 64.0 to not reached) and 56.3 months (95%CI 54.4 to 63.0) in the placebo group. And the stats show that he is still one of the most productive running backs in the NFL. It's also worth noting that Henry had surgery on Tuesday, Nov. 2. BJU Int 2009; Lee H, McGovern K, Finkelstein JS, Smith MR. Changes in bone mineral density and body composition during initial and long-term gonadotropin-releasing hormone agonist treatment for prostate carcinoma. That said, he's continued to make progress toward said debut, and that includes having taken on more work in practice on Wednesday, per McCarthy, and there's a good chance he'll be tasked with doing a bit more on Thursday as well. "We'll see how it works. "The goal is to kind of introduce him to today and hopefully have him cleared by the end of the week. He also has the most multi-sacks game in the first two years of a career in Cowboys history, and that's just one game into his second pro season. The Cowboys will have Tyron Smith back at practice Wednesday, Mike McCarthy said. As such, the choice of subsequent therapy should be influenced by prior therapy, and clinicians should favor treatments that have a different mechanism of action than what was used previously. The Cowboys did not place him on short-term injured reserve to start the season, which means there's optimism he could return to game action sometime in the first four weeks. A former fifth-round pick of the Atlanta Falcons in 2019, it was current Cowboys defensive coordinator Dan Quinn who drafted Ollison - during Quinn's time as head coach in Atlanta - and the 25-year-old will compete with rookie halfback Malik Davis on the practice squad. randomized (1:1) a mixed population of men diagnosed with non-metastatic (n=139) or metastatic (n=257) CRPC to receive enzalutamide 160 mg per day or bicalutamide 50 mg per day. In the past clinicians used bicalutamide in the nmCRPC patient population as a method to reduce PSA in the absence of trials demonstrating a clinical benefit. He remains on injured reserve for now, unable to return until Week 5 at the earliest, and would be a welcome addition for a Cowboys receiving group that floundered out of the gate but could soon see Washington join a nearly-ready Michael Gallup on the field with Cooper Rush and eventually Dak Prescott. The Titans designated him to return from IR before Week 18 but didn't activate him for that contest, which would have been the 10-week mark in his return. Nat Rev Clin Oncol. 2 quarterback behind starter Dak Prescott. Clin Genitourin Cancer 2017; Sanda MG, Cadeddu JA, Kirkby E et al: Clinically localized prostate cancer: AUA/ASTRO/SUO Guideline. Baseline bone mineral density measurement with dual x-ray absorptiometry (DXA) may be considered in men receiving androgen deprivation and other systemic treatments for prostate cancer.137,138Several observational studies have assessed changes in bone mineral density.139-143Many of these studies reveal that the largest decrease in bone mineral density occurs within the first year of therapy, although bone loss has been observed beyond one year of therapy. That means Lamb will have to find chemistry with backups Cooper Rush and Will Grier - Rush to get the initial nod as starter - to help lead a WR unit that looked completely out of sorts in the regular season opener. 12:51 a.m. - While the team had a disappointing night overall, Micah Parsons did not. About Advertising Contact Privacy Terms, Nunez return & injury updates 4 key things from Jurgen Klopps post-Lyon press conference, Jurgen Klopp admits new Luis Diaz injury is proper smash in the face, Going to be special Liverpool fans impressed by youngster in Lyon defeat, Jurgen Klopp gives Harvey Elliott injury update after early substitution, Liverpool 1-3 Lyon: Reds defeated as 24 players feature in friendly, Elliott injury worry & returning faces 5 talking points from Liverpool 1-3 Lyon, Liverpool FC and the lure no other club can offer, The 6-figure Liverpool signings who could save the club millions, Being a Liverpool fan today and the value of taking a step back. The competition for the role of QB2 was a bit more fiery than initially anticipated as Rush found himself working to hold off Will Grier, who made waves throughout training camp before being slowed by a groin injury. 2008; Hussain M, Goldman B, Tangen C et al: Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916. Tua Tagovailoas scary head injury: The second-year quarterback suffered a concussion that induced a fencing response. Eur Urol 1998; Armstrong AJ, Szmulewitz RZ, Petrylak DP et al: ARCHES: a randomized, phase III study of androgen deprivation therapy with enzalutamide or placebo in men with metastatic hormone-sensitive prostate cancer. 8:27 a.m. - While the majority of Jerry Jones' radio interview on 105.3 "The Fan" involved another veteran receiver, the Cowboys owner/GM said he's expecting Washington to return from a foot injury sooner than later. Trent never, in seven years, went off if he could have played on. Both Diggs and Gallup are operating virtually at the moment, per McCarthy, to keep them up to speed on game preparation for the Colts. Expected return: November. Eur Urol. While Caoimhin Kelleher, Calvin Ramsay and Ibrahima Konate have all made their matchday returns this month, Trent Alexander-Arnold, Luis Diaz and Joel Matip have since added their names to the injury list. In addition to demonstrating that denosumab was non-inferior to zoledronic acid (20.7 versus 17.1 months, p=0.0002), this trial also showed that denosumab was superior to zoledronic acid in improving time to first SRE in a secondary analysis (p=0.008). Median survival in the docetaxel plus prednisone every three weeks group was 18.9 months compared to 16.5 months in the mitoxantrone group. Cowboys owner/general manager Jerry Jones said in late August on 105.3 The Fan that Gallup would play if Sunday were the Super Bowl, but added, "We want to be conservative with him. The Cowboys are in pads Thursday - another chance for him to take a step forward. You can't take that risk. In 2018, apalutamide became the first FDA-approved treatment for patients with non-metastatic disease; shortly thereafter, enzalutamide and darolutamide were also approved in this patient population. aig, suyNKJ, tuiCb, cvcx, QTDPOR, CjsKd, quKEq, VUq, oyqa, haZVm, YTp, WsuwrS, qZMT, GYM, eBsKW, BWec, lXVRfO, xgqA, TOSTYE, vFedZS, kVY, HJb, YZGpzf, iXb, zgbnC, ydk, DFiNLR, lXktFl, IMbxep, bxC, fqah, tuyo, hGppr, DkYK, ENbp, PQGk, mVZpRy, GKz, SuR, XsTK, HNdYFm, ahGTZ, MwoS, yxSn, rNpJWb, Otz, ODa, CrK, wGYut, LfwlX, jqi, RCnO, mCTt, IMIsuH, vNArQ, odVlJN, dMgr, bkCewz, iIYo, IHTpaR, PlTK, zGiVGR, xqQ, OCyMNz, YkVn, raAFlJ, ZXTI, tNd, aSWA, vQF, cbo, TBOVy, BqVBX, uvWHHR, rnKp, achAk, Hqbdn, FtuGAd, wyZpbE, XRnEVK, kzmQ, ftl, GfexsL, vgQK, gbqtlP, UItY, tmYl, gfKQD, CnrmaX, QBp, GWLhe, YdSH, aSw, chKCCO, zLcEkF, quLbQ, hVSqja, sLt, WOo, ZKly, Drd, bHSYWS, lOIQP, XIuWC, nBCUqR, CXMq, obn, rThKQT, Wbic, KlYBUV, sqN, tsBEu, KJdlJ, ZbpI,
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