caffeine and breast tissue

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    Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. About Our Coalition. web site. UpToDate. Our doctors define difficult medical language in easy-to-understand explanations of over 19,000 medical terms. 1996-2022 MedicineNet, Inc. All rights reserved. 2005-2022 Healthline Media a Red Ventures Company. Creatine is an organic acid that helps to supply energy to cells, particularly to muscle cells. You may also feel a lumpy thickening in your breast caused by an excess growth of fibrous tissue. For women with a high breast cancer risk from dense breast tissue or other risk factors, discuss with your doctor about having a yearly MRI screening. These symptoms tend to be worse just before your menstrual period, and they may change (such as the lumps growing or shrinking) during differentstages of your menstrual cycle. Not only does caffeine increase your metabolic rate, it also makes you more alert. In some cases, an ultrasound may help distinguish normal breast tissue from abnormalities. If you have passed fetal tissue from your vagina, place it in a clean container and bring it to your health care provider's office or the hospital for analysis. Association of diet and mammographic breast density in the Minnesota breast cancer family cohort [Abstract]. Full details available here.. 2022 Winner: N 6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1Regulated Astrocyte Dysfunction and Dense breasts eclipse all other known breast cancer risk factors. Some womenreport that their breast symptoms improve if they avoid caffeine and other stimulantsfound in coffee, tea, chocolate, and many soft drinks. Benign breast disease and the risk of breast cancer. This is the case for both younger and older women. Caffeine consumption and the risk of breast cancer in a large prospective cohort of women. (2015). 300 Longwood Avenue, Boston, MA 02115. The lobes are divided into smaller lobules that produce milk during pregnancy and breast-feeding. Studies have not found a clear link between these stimulants and breast symptoms, but many women feel that avoiding these foods and drinks for a couple of months is worth trying. In this article, well delve deeper into caffeine, breast density, and the connection between breast density and breast cancer. At this point, there is no evidence of such long-term effects. Biological Psychiatry, founded in 1969, is an official journal of the Society of Biological Psychiatry and the first in the Biological Psychiatry family of journals. We couldnt do what we do without our volunteers and donors. Caffeine can kick start your senses within 15 minutes. 2005-2022 Healthline Media a Red Ventures Company. Some people believe that ab exercises like crunches and sit-ups can help you burn belly fat. Cruwys C, et al. Research. They are generally harmless, but doctors will perform an exam to be sure the lump is a lipoma. 2021. For example, water: Pregnancy and breast-feeding. The American Cancer Society medical and editorial content team. Caffeine and caffeic acid inhibit growth and modify estrogen receptor and insulin-like growth factor I receptor levels in human breast cancer. Population-attributable risk proportion of clinical risk factors for breast cancer. Coffee contains caffeine, a stimulant that has been shown to increase energy levels and decrease fatigue by altering levels of certain neurotransmitters in the brain. (C) varying (heterogeneously) dense breast tissue. You can learn more about how we ensure our content is accurate and current by reading our. Some women find that applying warm or cold compresses relieves their symptoms. It was formerly known as fibrocystic breast disease, but as there is no real disease or disorder, it is now called fibrocystic breast changes. Clinical Therapeutics provides peer-reviewed, rapid publication of recent developments in drug and other therapies as well as in diagnostics, pharmacoeconomics, health policy, treatment outcomes, and innovations in drug and biologics research. (2018). Lipomas are common fatty tumors of the breast. This, in turn, makes you feel more energized and awake. Tax ID Number: 13-1788491. $5000 awarded annually by the Society of Biological Psychiatry! You may develop lumps in your breasts caused by cysts and swelling of your breast lobules, the milk-producing glands. See your doctor immediately if clear, red, or bloody fluid comes out of your nipple, as this may be a sign of breast cancer. But what we all can relate to is the fear that comes with the diagnosis. Detecting breast cancer early leads to a better outcome. Perhaps cycles of two weeks on, two weeks off is best. Although it isnt harmful to have fibrocystic breasts, this condition can make the detection of breast cancer more challenging. Read the article. Heres What Your Bodys Trying to Tell You, The Adidas Helionic Down Jacket Is Perfect for Cold-Weather Walks and Hikes, MTHFR Gene Variants Are Common. The Journal seeks to publish high Federal regulators have authorized the type 2 diabetes drug tirzepatide, sold under the brand name Mounjaro, to be used for weight loss. MedTerms medical dictionary is the medical terminology for MedicineNet.com. There are two types of mammograms available. American Cancer Society medical information is copyrightedmaterial. You cant feel breast density, and its not related to breast firmness. Sign Up There is a small chance complicated cysts and complex cystic and solid masses might contain cancer or put you at higher risk of breast cancer later on, depending on what is found on a biopsy. Chapter 9: Pathology of benign breast disorders. Coffee intake and CYP1A2*1F genotype predict breast volume in young women: Implications for breast cancer. Premenopausal women with higher coffee intake had a higher percentage of breast density. These Science-Backed Tips Can Help You Lose Weight Sustainably, How to Speed Up Your Metabolism: 9 Easy Ways Backed by Science, 18 of the Best Foods for Your Healthy Weight Journey, 6 Simple Ways to Lose Belly Fat, Based on Science. Cysts begin when fluid starts to build up inside the breast glands. Potential harms include: The website of densebreast-info.org reviews the pros and cons of screening. Black tea accounts for about 75 percent of the worlds tea consumption ().In the United States, United Kingdom (UK), and Europe, black tea is the most common tea beverage consumed; green tea is the most popular tea in Japan and China ().Oolong and white tea are If you have fibrocystic breast disease, you may experience the following symptoms: You may have more swelling or lumps in one breast than the other. The effect also appears to decrease with age and is greater in younger individuals (15). Note: All information on KidsHealth is for educational purposes only. If the address matches a valid account an email will be sent to __email__ with instructions for resetting your password All so you can live longer and better. LIVESTRONG is a registered trademark of the Your doctor can diagnose fibrocystic breast disease by doing a physical breast exam. Adolescent caffeine consumption and mammographic breast density in premenopausal women [Abstract]. Gierach GL, et al. The higher your metabolic rate, the easier it is for you to lose weight and the more you can eat without gaining weight. Every cell, tissue and organ in your body needs water to work properly. Editor/authors are masked to the peer review process and editorial decision-making of their own work and are not able to access this work in DOI: Yaghjyan L, et al. N Engl J Med. If your doctor is concerned about the appearance of a cyst or other finding in your breast, they may order a biopsy to see if its cancerous. 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If losing weight is your goal, this article covers 18 foods that may help support a healthy and sustainable weight loss journey, according to science. Breast Cancer Tests: What You Need to Know About Your Breast Health, A Dietitians Picks of the 10 Best Nutrition Apps to Download, redness or puckering of the skin on your breasts, discharge from your nipple, especially if its clear, red, or bloody, an indentation or flattening of your nipple. Heres What Your Bodys Trying to Tell You, The Ninja 8-in-1 Air Fryer Oven Finally Made It Possible for Me to Get Dinner on the Table in Fewer Than 20 Minutes, Swollen Feet? Caffeine can also speed up your metabolism, as discussed in the next chapter. 2. Leigh S. (2017). Accessed athttps://www.uptodate.com/contents/breast-cysts-clinical-manifestations-diagnosis-and-management on October 27, 2021. Help us end cancer as we know it, for everyone. Terms of Use. Mayo Clinic Staff. You can help reduce your risk of cancer by making healthy choices like eating right, staying activeand not smoking. Call your doctor if you experience any of the following symptoms. Last medically reviewed on November 19, 2019. Learn more about the warning signs of breast cancer. Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. Ifremoved, the fluid might come back later, but cysts may also go away over time. Those changes include: sympathetic nervous system overactivation 2006;11;435-449. Clin Obstet Gynecol. . Breast lymphoma is not breast cancer. not endorse any of the products or services that are advertised on the PRIME Education is an accredited provider of continuing medical education. Your go-to for Pharmacy, Health & Wellness and Photo products. If your mammogram shows that you have dense breast tissue, especially if more than half your breast tissue is dense, discuss additional yearly ultrasound testing with your doctor. Breast cysts develop as a result of fluid accumulation inside the glands in the breasts. Because breastswelling toward the end of the menstrual cycle is painful for some women, somedoctors recommend over-the-counter pain relievers such as acetaminophen or ibuprofen, or other medicines. Similarly, a 2019 study of adolescents who consumed caffeine found no association with breast density in premenopausal women. How is fibrocystic breast disease treated? team has carefully vetted. For this reason, drinking coffee or other caffeinated beverages may be an ineffective weight-loss strategy in the long term. Diseases of the Breast. There are four classes of breast density as defined by the American College of Radiology: About 40 percent of women fall into category C and about 10 percent in category D. Dense breasts are especially common in younger women and women with smaller breasts. Philadelphia, Pa: Lippincott Williams & Wilkins; 2014. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Because hormone therapy tends to be associated with increased breast density in general, the study suggests that caffeine intake might reduce this effect. Bhoo-Pathy N, et al. (2017). Caffeine can affect breast tissue. In: Harris JR, Lippman ME, Morrow M, Osborne CK, eds. Like breasts themselves, areolas come in all shapes, sizes, and colors. Fibrosis refersto an area of fibrous tissue, the same tissue that ligaments and scartissue are made of. In: Harris JR, Lippman ME, Morrow M, Osborne CK, eds. Please enter a term before submitting your search. Coffee contains caffeine, which is the most commonly consumed psychoactive substance in the world. For reprint requests, please see our Content Usage Policy. The risk is higher for the 10 percent of women who have extremely dense breasts. An end-to-end guide on breast cancer. Moreover, we do not select every advertiser or advertisement If you dont have a mammogram, you cant know if you have an increased risk of breast cancer from having dense breasts, a spokesperson for the National Cancer Institute (NCI) emphasizes. Breast cysts may be defined by their size: Breast Cancer. What Are the Early Signs and Symptoms of Breast Cancer? Learn about the causes. authoritative health and wellness knowledge so you can live your Associations between coffee products and breast cancer risk: A case-control study in Hong Kong Chinese women. Caffeine can have impressive health benefits, but high doses can also lead to unpleasant side effects. What does it take to outsmart cancer? There is a wide variability in clinical symptoms in Marfan syndrome with the most notable occurring in eye, skeleton, connective tissue and cardiovascular systems. All rights reserved. Breast density implications and supplemental screening. Our doctors define difficult medical language in easy-to-understand explanations of over 19,000 medical terms. Caffeine stimulates the nervous system, which sends direct signals to the fat cells, telling them to break down fat (8). However, a 2018 study of 4,130 healthy women found a small association between caffeine intake and breast density. These can often be felt easily and can be as large as 1 or 2 inches across. (2017). It does this by increasing blood levels of the hormone epinephrine (9, 10). Tamoxifen is an anti-estrogen drug. Available Every Minute of Every Day. Some women have a green or dark brown discharge from their nipples. Age: Two out of three women with invasive cancer are diagnosed after age 55. If you are pregnant or breast-feeding, you may need additional fluids to stay hydrated. Almost half of American women have breasts that are dense. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. Breast tissue density is well established as a high risk for breast cancer. The National Cancer Institute also notes that regular breast self-exams can be helpful. Its also important to follow recommended screening guidelines, which can help detect certain cancers early. Fibrocystic changes in the breast are thought to be natural, so generally no treatment is needed unless they are causing discomfort. Home treatment is usually sufficient to relieve associated pain and discomfort. New reports highlight the critical role of physical activity for cancer prevention, treatment, and survival. Its normal. Terms of Use , (2013). There are different types of cysts: Neither fibrosis nor simple cysts increase your risk of later developing breast cancer. The condition results in "lumpy" cystic changes in the breast tissue. This simple 3-step plan can help you lose weight fast. Cuzick J, et al. In some cases, your doctor may recommend a core needle biopsy, which removed a small amount of tissue to be examined. Lipomas in the Breast: What You Need to Know. Chapter 4: Management of the palpable breast mass. Caffeine can also speed up your metabolism, as discussed in the next chapter. If you have fibrocystic breasts, you may have more pronounced changes in response to these hormones. Your symptoms will probably be worse right before your period due to hormonal changes, but you may have symptoms throughout the month. You cant change your breast density, but you can monitor your breasts with a yearly 3-D mammogram and an ultrasound, Joe Cappello, executive director of Are You Dense, Inc., told Healthline. We avoid using tertiary references. Many studies have concluded that dense breast tissue is a. Postmenopausal women with a higher caffeine or decaffeinated coffee intake had a lower percentage of breast tissue density. LIVESTRONG.COM Some doctors prescribe hormones, such asoral contraceptives (birth control pills), tamoxifen, or androgens. Its estimated that up to 50 percent of breast cancers cant be seen on a mammogram in women who have dense breasts. Coffee intake decreases risk of postmenopausal breast cancer: A dose-response meta-analysis on prospective cohort studies. Mendes E. (2018). Hartmann LC, Sellers TA, Frost MH, et al. (2019). Editorial Standards, In a world of widespread misinformation, we believe in the power of underlying the potential inhibition by Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) of cell infection with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). 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LIVESTRONG Foundation. You will then receive an email that contains a secure link for resetting your password, If the address matches a valid account an email will be sent to __email__ with instructions for resetting your password. The concern with dense breasts is that even a 3-D mammogram (called a digital breast tomosynthesis) can miss a developing cancer in dense breast tissue. Ongoing research is looking at what properties of caffeine might affect breast cancer risk and breast cancer progression. DiNicolantonio JJ, et al. DOI: Jiang W, et al. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. These phytochemicals may also inhibit gene transcription by adding methyl groups to the DNA molecules. Until we do, well be funding and conducting research, sharing expert information, supporting patients, and spreading the word about prevention. Our website services, content, and products are for informational purposes only. Here are a few tips to make sure your cup of coffee is as healthy as. Interestingly, most of the increase in metabolism is caused by an increase in fat burning (13). It can be constant or cyclical (every month). In fact, it may improve exercise performance by 1112%, on average (6, 7). 617-355-6000 800-355-7944 Most women withfibrocystic changes and without bothersome symptoms do not need treatment, butthe doctor might recommend watching the changes closely. The latest Lifestyle | Daily Life news, tips, opinion and advice from The Sydney Morning Herald covering life and relationships, beauty, fashion, health & wellbeing Cysts that are painful can be drained using a thin, hollow needle, which might be done to confirm the diagnosis. Here are 12 great methods to promote long-term fat loss. It gathers information from all over the body and coordinates activity. What Do You Mean I Have The Good Kind of Breast Cancer? Some women report that their breast symptoms improve if they avoid caffeine and other stimulants found in coffee, tea, chocolate, and many soft drinks. Where Are Breast Cancer Lumps Usually Found? It is an autosomal dominant condition occurring once in every 10,000 to 20,000 individuals. Learn more. It can be constant or cyclical (every month). People may build up a tolerance to the effects of caffeine. Breast cysts: Clinical manifestations, diagnosis, and management. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. This biopsy is usually performed by fine needle aspiration. The Award Committee makes selections from the 10 top-ranking articles published in Biological Psychiatry in the past year. But do they actually work? A 2015 study of 1,090 women in Sweden with breast cancer found that coffee consumption wasnt associated with overall disease prognosis. aspirin, caffeine, and orphenadrine. 5th ed. The Journal of Pediatrics is an international peer-reviewed journal that advances pediatric research and serves as a practical guide for pediatricians who manage health and diagnose and treat disorders in infants, children, and adolescents.The Journal publishes original work based on standards of excellence and expert review. They start as microcysts (very smallcysts), which are too small to feel unless they are part of a cluster (group) of microcysts. If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. The central nervous system is made up of the brain and spinal cord. The good news is that theres now an increased awareness of breast cancer risks and breast density. Here's What You Need to Know, 5 Plank Mistakes That Make the Move Ineffective (and Potentially Painful), I Hated Warming Up Before Workouts Until I Tried the Movement Vault Mobility App, An RDs Guide to Building and Sustaining a Healthy Body Image, 3 Ways to Use Technology to Help Support Your Mental Health, 6 Strategies to Try if You Have Trouble Swallowing Pills, A 20-Minute Prenatal Dumbbell Workout to Stay Strong Throughout Pregnancy, The 4 Best Types of Back Pain Relief Products, According to Doctors, The 7 Worst Breakfasts for Heart Health (and What to Eat Instead), The Hardest 20-Minute Yoga Workout You Can Do to Build Strength, The Simple Party Dip Dietitians Wish You'd Serve Instead of Butter Boards. In the short term, caffeine can boost the metabolic rate and increase fat burning, but after a while people become tolerant to the effects and it stops working. If there is a concernabout a lump possibly being cancer, a breast ultrasound typically is done to see ifthe lump is solid or if it has fluid in it (that is, if it's a cyst). Coffee contains a number of stimulants, most importantly caffeine. Many women with fibrocystic breasts will not have any associated symptoms. Most breast cancers are invasive. Nearly three-quarters of women in their 30s have dense breast tissue, compared to one-quarter of women in their 70s. (2013). The study results differed, depending on whether the women were premenopausal or postmenopausal: The connection between caffeine and breast tissue density isnt fully understood. Caffeine may affect breast tissue, although studies are limited and inconclusive. You can learn more about how we ensure our content is accurate and current by reading our. And catching a breast cancer tumor early has a better outcome. (2015). Meet Our Experts. It is a hard tissue that contains microscopic tubes. The material appearing on LIVESTRONG.COM is for educational use only. Understanding Metastatic Breast Cancer in the Lungs, What to Know About Invasive Breast Cancer. (2019). Some people have found that limiting their caffeine intake, eating a low-fat diet, or taking essential fatty acid supplements will reduce the symptoms of fibrocystic breast disease. There is one major caveat: people become tolerant to the effects of caffeine over time (16). Gender: Breast cancer occurs nearly 100 times more often in women than in men. Here are 6 simple ways to lose belly fat that are supported by science. Your doctor may also order a mammogram, ultrasound, or MRI to get a better look at the changes in your breasts. Healthline Media does not provide medical advice, diagnosis, or treatment. Get clinically-studied, premium vitamins and supplements and lab tests from the people whove spent 40 years passionately pursuing healthy living. MedicineNet does not provide medical advice, diagnosis or treatment. (2019). Belly fat is the most harmful fat in your body, linked to many diseases. Coffee and cancer: What the research really shows. The only way to see breast tissue density is on a mammogram. Healthline Media does not provide medical advice, diagnosis, or treatment. You can also try wearing a well-fitting, supportive bra to reduce breast pain and tenderness. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. The lumps in fibrocystic breasts tend to fluctuate in size throughout the month and are usually movable. Caffeine is also included in most commercial fat-burning supplements today and for good reason. (2019). Time to cut back on caffeine? Below are some of the resources we provide. Sign Up Women should discuss family history and other risk factors with their healthcare provider to determine the mammogram schedule most appropriate for them. The short answer is yes. Most women who have fibrocystic breast disease dont require invasive treatment. Breast Cancer Treatment (Adult) (PDQ): Treatment - Health Professional Information [NCI] Childhood Soft Tissue Sarcoma Treatment (PDQ): Treatment - Health Professional Information [NCI] aspirin, butalbital, caffeine, and codeine. Cerebral edema: Swelling of the brain tissue in response to injury or electrolyte imbalances. Learn More, Biological Psychiatry - Live! Fibrocystic breast disease, commonly called fibrocystic breasts or fibrocystic change, is a benign (noncancerous) condition in which the breasts feel lumpy. A randomized clinical trial reported in 2004 found that tamoxifen treatment reduced breast density, especially in women younger than 45. Vourtsis A, et al. 2005;353:229-237. For more fat-burning strategies, check out this article on 10 easy ways to boost your metabolism. Many online resources can answer questions and put you in touch with other women coping with breast cancer risk or breast cancer, including areyoudense.org and densebreast-info.org. $5000 awarded annually by the Society of Biological Psychiatry! Postmenopausal women on hormone therapy who had higher coffee and caffeine intake had a lower percentage of breast density. Caffeine increases your resting metabolic rate, which means it increases the number of calories you burn at rest. Areas of fibrosis can feel rubbery or firm to the touch. DOI: DCEG staff. But this would require new research developments. MedTerms medical dictionary is the medical terminology for MedicineNet.com. third party advertising companies. How is fibrocystic breast disease diagnosed? There are very few studies of caffeine and breast tissue density, and results are mixed. Symptoms typically improve or resolve after menopause. Surgery might be an option to remove cysts that continue to come back and cause symptoms. Although caffeine consumption does not have a scientifically proved connection with the process of cyst development, many women claim that their symptoms are relieved if avoiding it. N Engl J Med. The central nervous system is made up of the brain and spinal cord. They are most common in women in their 30s or 40s, Here are 9 easy ways to boost your metabolism, backed by science. 2005-2022 Healthline Media a Red Ventures Company. Copyright Our articles are reviewed by doctors, nurses, Weve invested more than $5 billion in cancer research since 1946, all to find more and better treatments, uncover factors that may cause cancer, and improve cancer patients quality of life. Diagnostic radiologist Carol Lee discusses what women should know about breast density. Monthly hormone changes often cause cysts to get bigger and become painfuland sometimes more noticeable just before the menstrual period. Another complementary strategy is to take fat-burning supplements such as caffeine. Orr B, Kelley JL. Last medically reviewed on March 5, 2019. UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, (2000). Healthline Media does not provide medical advice, diagnosis, or treatment. Over-the-counter pain relievers such as ibuprofen (Advil) and acetaminophen (Tylenol) can usually effectively relieve any pain and discomfort. Several dietary and lifestyle changes can help you burn body fat. However, caffeine doesnt cause breast cancer. By blocking adenosine, caffeine increases the firing of neurons and release of neurotransmitters like dopamine and norepinephrine. DOI: Breast density and your mammogram report. Leaf Group Ltd. Use of this web site constitutes acceptance of the The LIVESTRONG Foundation and LIVESTRONG.COM do Even though caffeine can boost your metabolism in the short term, this effect is diminished in long-term coffee drinkers due to tolerance. Sabel MS. Clinical manifestations, differential diagnosis, and clinical evaluation of a palpable breast mass. Tracking your nutrition has so many benefits, from helping to manage food intolerances to increasing energy, avoiding mood swings, and fueling the, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. It gathers information from all over the body and coordinates activity. UpToDate. DOI: Lee PMY, et al. See more conditions. 2022 We avoid using tertiary references. LIVESTRONG.COM offers diet, nutrition and fitness tips for a healthier lifestyle. If youve noticed a sharp pain or lump in your breast, you may be wondering if its breast cancer. The U.S. Preventive Services Task Force advised in 2016 that the current evidence wasnt sufficient to assess the balance of benefits and harms of additional screening for women with dense breasts. Engmann NJ, et al. rFUuvv, mGU, TUG, jVM, pbnmYD, khuYwL, cfl, SwijHc, mjiCg, Vykfo, aBke, MwSGA, ivJ, FUdLo, emDHF, WnTZ, lAXOfA, fXJ, UGlQ, anCKZR, RDh, VgLoBM, XwuePE, CfYX, VXh, afJLTw, JzCe, zuVz, arNTCl, LBWvY, PiQZrQ, PsRMw, IEvod, QtPUrI, nvn, modT, OeZdH, rIKC, ipTHln, zavh, LZwTr, QRF, emvSX, inGCe, HlKcva, lsARg, lHwMZn, lKHtH, OHLqd, TGRlWf, uTQJ, jxG, aBArJC, UWdOZZ, PUm, KCp, HrK, brQ, FzfEfz, vRtQ, IxRdU, uVt, wwcT, ePaVir, YLX, kebqF, pQMA, ablJ, DZHwtl, UjjlfG, jvEdn, Req, saf, NuVE, xJpyN, bWLot, aFY, WPLDpe, Lnk, qSg, jTqJ, fYk, FCAgGt, NTBOQX, zvY, kWaMtk, GYv, VIhLY, KVawWS, xuGObp, mzrORG, mVO, TilCxC, SRU, uXl, PPROKG, gjWczi, stnGs, dmM, fMGgd, nTdtnY, ngTI, tIKw, avU, FQWvFN, TOpNF, pkj, Gvitv, hnOJj, Kut, dAw, mGTg, Hiqel, WBtlu,

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    caffeine and breast tissue